COMPLETED PROJECTS
We have now published 5 studies which were designed, delivered, and disseminated via our network. All 5 studies had an international reach with centres recruiting across Europe. The collaborators helped deliver meaningful real-world research to benefit patients with peripheral arterial disease. The following 5 articles are available online and in print:
ENSUPRO
Bypass surgery plays a key role in complex lower limb lesions. However, there is a lack of evidence regarding the management of symptomatic prosthetic bypass graft (PBG) occlusion. This study aimed to report outcomes following open, hybrid, or endovascular management of patients presenting with symptomatic PBG occlusion.
RANDOM-STOP
The aim was to assess the proportion of patients undergoing endovascular therapy for femoropopliteal arterial disease (F-P) who would be eligible to take part in seven major randomised controlled trials (RCTs) that investigated the efficacy of some of the currently available paclitaxel based (PTX) devices used in this clinical context. Various RCTs have shown a potential clinical benefit from the use of paclitaxel in F-P endovascular therapy. Nonetheless, patients enrolled were highly selected and the generalisability of these findings in pragmatic cohorts is unclear.
EMOPOP
International registry on isolated popliteal artery endovascular treatments. This was a multicentre study across several countries in Europe. EMOPOP represents the largest cohort study to date reporting outcomes after endovascular treatment(s) for isolated popliteal artery disease. The study was completed in less than a year, reporting outcomes relating to the treatment of thousands of patients. Our team pioneered a novel type of statistical analysis in order to report/compare results using several different treatment approaches within the popliteal artery. The full published work is now available on the Journal of Vascular Surgery.
COBRA study
Covered vs. Bare Metal Stents in the Reconstruction of the Aortic Bifurcation. This was the 1st major RCPAD study involving several sites across the United Kingdom and Europe. This observational study assessed outcomes following endovascular treatment of complex aorto-iliac occlusive lesion with a variety of techniques and devices. Our network supported data collection, analysis, and dissemination (including statistical analyses to assess treatments’ interactions). Two manuscripts have now been published as a result, one from centres across the United Kingdom, describing a UK-wide experience relating to these endovascular techniques, and one from across Europe.
BUBH
(bullying, undermining, and harassment) in the vascular healthcare environment. RCPAD completed an international survey of vascular healthcare professionals (578 participants) to assess the prevalence of BUBH behaviours in the vascular workplace. This is the first international work of this nature. Results are currently in publication and are expected to shape future policy-making in this wider area.